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produced a sustained IGF-1 elevation (40-50% above baseline for 14 days) without recapitulating the pulsatile GH architecture

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10.1007/s00125-013-3145-0 74 HolstJ

Bahari A, Akoh C (2018b) Texture, rheology and fat bloom study of chocolates made from cocoa butter equivalent synthesized from illipe butter and palm mid-fraction

In general, disordered domains are unsuitable targets for potent peptide binding because of the lack of well-defined binding surfaces, conformational flexibility, and associated entropic penalties 60,61